BBLS, MB BCh BAO, MRCPI
Clinical Assistant Professor, Respiratory Medicine, University of Calgary
Director, Asthma and COPD Program, Rockyview Hospital
Dr. Mitchell's clinical interests are in asthma, Chronic Obstructive Pulmonary Disease (COPD), chronic eosinophilic airways disease, autoimmune pulmonary diseases, Sarcoidosis, Pulmonary Thromboembolic disease and airways disease in pregnancy. His research interests encompass asthma, COPD, eosinophilic pulmonary diseases, transitional clinics, atopic and allergic disease.
Dr. Mitchell trained as a specialist in Respiratory and Internal Medicine in Ireland. He undertook a two-year clinical and research fellowship at McMaster University under Dr. Paul O’Byrne, which entailed translational research in airway inflammation and servicing both general respiratory and airway inflammation clinics. He also completed a two-year Medical Doctorate thesis on the role of IL-33 in allergic asthma. He has authored numerous peer reviewed research manuscripts and co-authored a book chapter on asthma.
Mitchell P, Leigh R.A drug safety review of treating eosinophilic asthma with monoclonal antibodies. Expert Opin Drug Saf. 2019 Oct 21:1-10. doi: 10.1080/14740338.2019.1675634. [Epub ahead of print].
Lim R, Marciniak SJ, Marcadier J, Rassl D, Mitchell PD. Time Is of the Essence: A Young Man with Recurrent Pneumothorax and Cavitating Lung Lesions. Ann Am Thorac Soc. 2018 Aug;15(8):988-991. doi: 10.1513/AnnalsATS.201712-968CC.
Satia I, Watson R, Scime T, Dockry RJ, Sen S, Ford JW, Mitchell PD, Fowler SJ, Gauvreau GM, O'Byrne PM, Smith JA. Allergen challenge increases capsaicin-evoked cough responses in patients with allergic asthma. J Allergy Clin Immunol. 2019 Sep;144(3):788-795.e1. doi: 10.1016/j.jaci.2018.11.050. Epub 2019 Jan 17.
Mitchell PD, Salter BM, Oliveria JP, El-Gammal A, Tworek D, Smith SG, Sehmi R, Gauvreau GM, O Apos Byrne PM. Allergen challenge increases capsaicin-evoked cough responses in patients with allergic asthma. J Allergy Clin Immunol. 2019 Sep;144(3):788-795.e1. doi: 10.1016/j.jaci.2018.11.050. Epub 2019 Jan 17.
Canonica GW, Senna G, Mitchell PD, O'Byrne PM, Passalacqua G, Varricchi G. Therapeutic interventions in severe asthma. World Allergy Organ J. 2016 Nov 28;9(1):40. eCollection 2016. Review.
Mitchell PD, Salter BM, Oliveria JP, El-Gammal A, Tworek D, Smith SG, Sehmi R, Gauvreau GM, Butler M, O'Byrne PM. Glucagon-like peptide-1 receptor expression on human eosinophils and its regulation of eosinophil activation. Clin Exp Allergy. 2017 Mar;47(3):331-338. doi: 10.1111/cea.12860. Epub 2017 Jan 28.
Mitchell PD, El-Gammal AI, O'Byrne PM. Anti-IgE and Biologic Approaches for the Treatment of Asthma. Handb Exp Pharmacol. 2017;237:131-152. doi: 10.1007/164_2016_65. Review.
Mitchell PD, O'Byrne PM. Epithelial-Derived Cytokines in Asthma. Chest. 2017 Jun;151(6):1338-1344. doi: 10.1016/j.chest.2016.10.042. Epub 2016 Nov 3. Review.
Mitchell PD, O'Byrne PM. Biologics and the lung: TSLP and other epithelial cell-derived cytokines in asthma.Pharmacol Ther. 2017 Jan;169:104-112. doi: 10.1016/j.pharmthera.2016.06.009. Epub 2016 Jun 27. Review.
Mitchell PD, O'Byrne PM. Surfactant Protein-D and Asthma. Chest. 2016 May;149(5):1121-2. doi: 10.1016/j.chest.2015.12.038.
Mitchell PD, El-Gammal AI, O'Byrne PM. Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma. Clin Pharmacol Ther. 2016 Jan;99(1):38-48. doi: 10.1002/cpt.284. Epub 2015 Nov 18. Review.
All CIC publications featuring Dr. Mitchell as a co-author are listed below.
| Author(s) | Year | Title | Journal |
|---|---|---|---|
| Mitchell PD, Salter BM, Oliveria JP, El-Gammal A, Tworek D, Smith SG, Sehmi R, Gauvreau GM, Butler M, O'Byrne PM | 2016 |
Clinical and Experimental Allergy |
|
| Tang W, Smith SG, Salter B, Oliveria JP, Mitchell P, Nusca GM, Howie K, Gauvreau GM, O'Byrne PM, Sehmi R | 2016 |
International Archives of Allergy and Immunology |
|
| El-Gammal A, Oliveria JP, Howie K, Watson R, Mitchell P, Chen R, Baatjes A, Smith S, Al-Sajee D, Hawke TJ, Killian KJ, Gauvreau GM, O'Byrne PM | 2016 |
Allergen-induced Changes in Bone Marrow and Airway Dendritic Cells in Subjects with Asthma |
American Journal of Respiratory and Critical Care Medicine |
| Salter BM, Oliveria JP, Nusca G, Smith SG, Tworek D, Mitchell PD, Watson RM, Sehmi R, Gauvreau GM | 2016 |
IL-25 and IL-33 induce Type 2 inflammation in basophils from subjects with allergic asthma |
Respiratory Research |
| Mitchell PD, O'Byrne PM | 2016 | Surfactant protein-D and asthma | CHEST |
| Mitchell PD, El-Gammal AI, O'Byrne PM | 2015 | Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma | Clinical Pharmacology and Therapeutics |