Louis-Philippe Boulet

MD, FRCPC, FCCP

Professor, Department of Medicine, Laval University

Lung Specialist, l’Institut universitaire de cardiologie et de pneumologie de Québec (iuCPQ)

Chairholder, Knowledge Transfer, Training and Prevention Chair on Respiratory and Cardiovascular Health

Dr. Boulet is a respirologist at the Institut de cardiologie et de pneumologie de Québec (Quebec Heart and Lung Institute), a professor of medicine at the Department of Medicine of Laval University, and holds a chair in Knowledge Translation, Education and Prevention in Respiratory and Cardiorespiratory Health at Laval University. He is also Chair of the Board of Directors of the Global Initiative for Asthma (GINA); first vice-president of InterAsma, the Global Asthma Association; and a member of many Canadian and International medical societies and guidelines committees. He is past chair of the Canadian Thoracic Society (CTS) and of the CTS Respiratory Guidelines Committee, and was a founding member of the Quebec Respiratory Health Education Network.

In addition to his clinical practice and teaching, Dr. Boulet runs a research program focused mainly on the themes of asthma phenotypes; airway responses, inflammation and remodelling; respiratory allergy; respiratory health of athletes; and knowledge translation and health education. His research seeks to establish links between basic and clinical science in the field of asthma and respiratory allergy. He has undertaken collaborative studies on the mechanisms of asthma development, with a particular focus on: airway function; inflammation and structure changes in high-risk groups; and the influence of obesity, high-level exercise training (athletes), exposure to substances such as allergens and occupational agents, and various therapeutic and educational interventions.

Dr. Boulet is frequently invited as a speaker at national and international meetings. He has written more than 650 medical publications, in addition to 633 abstracts and 43 book chapters, and he has edited/authored 17 books.


All CIC publications featuring Dr. Boulet as a co-author are listed below.

Total Records Found: 28, showing 100 per page
Author(s)YearTitleJournal
Gauvreau GM, FitzGerald JM, Boulet L-P, Watson R, Hui L, Villeneuve H, Scime T, Schlatman A, Obminski C, Kum J, Boehme S, Ly TW, Bacon K, O'Byrne PM 2018 The Effects of a CCR3 Inhibitor, AXP1275, on Allergen-Induced Airway Responses in Adults with Mild-to Moderate Atopic Asthma Clinical & Experimental Allergy
Singh A, Shannon CP, Kim YW, Yang CX, Balshaw R, Cohen Freue GV, Gauvreau GM, FitzGerald JM, Boulet L-P, O'Byrne PM, Tebbutt SJ 2018 Novel blood-based transcriptional biomarker panels predict the late phase asthmatic response American Journal of Respiratory and Critical Care Medicine
Revez JA, Killian KJ, O'Byrne PM, Boulet LP, Upham JW, Gauvreau GM, Ferreira MAR 2018 Sputum cytology during late-phase responses to inhalation challenge with different allergens Allergy
Nair P, Martin JG, Cockcroft DC, Dolovich M, Lemiere C, Boulet LP, O'Byrne PM 2017 Airway Hyperresponsiveness in Asthma: Measurement and Clinical Relevance Journal of Allergy and Clinical Immunology: In Practice
Blais C, Cockcroft DW, Veilleux J, Boulay ME, Boulet L-P, Gauvreau GM, Scime TX, Watson RM, O’Byrne PM, Davis BE 2017 Methacholine challenge: comparison of airway responsiveness produced by a vibrating mesh nebulizer versus a jet nebulizer Journal of Aerosol Medicine and Pulmonary Drug Delivery
Gauvreau GM, Boulet LP, Leigh R, Cockcroft DW, Davis BE, Mayers I et al. 2016

Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting allergen-induced early asthmatic responses

Journal of Allergy and Clinical Immunology

Todd CM, Salter BM, Murphy DM, Watson RM, Howie KJ, Milot J, Sadeh J, Boulet LP, O'Byrne PM, Gauvreau GM 2016

The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects

Pulmonary Pharmacology and Therapeutics

Gauvreau GM, Boulet LP, FitzGerald JM, Cockcroft DW, Davis BE, Leigh R, Tanaka M, Fourre JA, Tanaka M, Nabata T, O'Byrne PM 2016

A dual CysLT1/2 antagonist attenuates allergen-induced airway responses in subjects with mild allergic asthma

Allergy

Smith SG, Chen R, Kjarsgaard M, Huang C, Oliveria JP, O'Byrne P, Gauvreau G, Boulet L-P, Lemiere C, Martin JG, Nair P, Sehmi R. 2015

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia

Journal of Allergy & Clinical Immunology

Ellis A, Soliman M, Steacy L, Boulay M, Boulet L, Keith P, Vliagoftis H, Waserman S, Neighbour H 2015

The Allergic Rhinitis – Clinical Investigator Collaborative (AR-CIC): nasal allergen challenge protocol optimization for studying AR pathophysiology and evaluating novel therapies

Allergy, Asthma & Clinical Immunology

Boulet LP, Gauvreau GM, Cockcroft DW, Davis B, Vachon L, Cormier Y, O'Byrne PM 2015

Effects of ASM-024, a modulator of acetylcholine receptor function, on airway responsiveness and allergen-induced responses in patients with mild asthma

Canadian Respiratory Journal

Boulet LP, Gauvreau G, Boulay ME, O'Byrne P, Cockcroft DW 2015

Allergen-induced early and late asthmatic responses to inhaled seasonal and perennial allergens

Clinical & Experimental Allergy

Gauvreau GM, Boulet LP, Leigh R, Cockcroft DW, Killian KJ, Davis BE, Deschesnes F, Watson RM, Swystun V, Mårdh CK, Wessman P, Jorup C, Aurivillius M, O'Byrne PM 2015

A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses

American Journal of Respiratory and Critical Care Medicine

Gauvreau GM, Harris JM, Boulet LP, Sheerens H, FitzGerald JM, Putnam WS, Cockcroft DW, Davis BE, Leigh R, Zheng Y, Dahlén B, Wang Y, Maciuca R, Mayers I, Liao XC, Wu LC, Matthews JG, O'Byrne PM. 2014

Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production

Science Translational Medicine

Gauvreau GM, O'Byrne PM, Boulet L-P, Wang Y, Cockcroft DW, Bigler J, FitzGerald JM, Boedigheimer M, Davis BE, Dias C, Gorski KS, Smith L, Bautista E, Comeau MR, Leigh R, Parnes JR. 2014

Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

The New England Journal of Medicine

Gauvreau GM, Boulet L-P, Cockcroft DW, FitzGerald JM, Mayers I, Carlsten C, Laviolette M, Killian KJ, Davis BE, Larché M , Kipling C , Dua B , Mosesova S , Putnam W , Zheng Y, Scheerens H, McClintock D , Matthews J, O'Byrne PM 2014

OX40L blockade on allergen-induced airway responses in subjects with mild asthma

Clinical Experimental Allergy

Singh A, Yamamoto M, Kam SHY, Ruan J, Gauvreau GM, O'Byrne PM, FitzGerald JM, Schellenberg R, Boulet L-P, Wojewodka G, Kanagaratham C, De Sanctis J, Radzioch D, Tebbutt SJ. 2013

Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses

PLOS ONE

Singh A, Cohen Freue GV, Oosthuizen JL, Kam SHY, Ruan J, Takhar M, Gauvreau GM, O'Byrne PM, FitzGerald JM, Boulet L-P, Borchers CH, Tebbutt SJ. 2012 Plasma proteomics can discriminate isolated early from dual responses in asthmatic individuals undergoing an allergen inhalation challenge

Proteomics ? Clinical Applications

Yamamoto M, Singh A, Ruan J, Gauvreau GM, O'Byrne PM, Carlsten C, FitzGerald JM, Boulet L-P, Tebbutt SJ. 2012

Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge

BMC Genomics

Lougheed MD, Lemière C, Ducharme FM, Lickai C, Dell SD, Rowe BH, Fitzgerald M, Leigh R, Watson W, Boulet L-P. 2012 Canadian Thoracic Society 2012 Guideline Update: Diagnosis and Management of Asthma in Preschoolers, Children and Adults: Executive Summary

Canadian Respiratory Journal

Gauvreau GM, Boulet LP, Cockcroft DW, Fitzgerald JM, Carlsten C, Davis BE, Deschesnes F, Duong M, Durn BL, Howie KJ, Hui L, Kasaian MT, Killian KJ, Strinich TX, Watson RM, Y N, Zhou S, Raible D, O'Byrne PM. 2011

The effects of IL-13 blockade on allergen-induced airway responses in mild atopic asthma

American Journal of Respiratory and Critical Care Medicine

Rousseau M-C, Boulay M-E, Goronfolah L, Denburg J, Keith P, Boulet L-P. 2011

Comparative responses to nasal allergen challenge in allergic rhinitic subjects with or without asthma

Allergy, Asthma & Clinical Immunology

Gaurvreau GM, Boulet LP, Cockcroft DW, FitzGerald JM, Carlsten C, Davis BE, Deschesnes F, Duong M, Durn BL, Howie KJ, Hui L, Kasaian MT, Killian KJ, Strinich TX, Watson RM, Zhou S, Raible D, O'Byrne PM. 2010

Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma

American Journal of Respiratory and Critical Care Medicine

Davis BE, Illamperuma C, Gauvreau GM, Watson RM, O'Byrne PM, Deschesnes F, Boulet LP, Cockcroft DW. 2009

Single dose desloratadine and montelukast and allergen-induced late airway responses

European Respiratory Journal

Boulet L-P, Lemière C, Gauvreau GM, Olivenstein R, Lougheed D, Paradis B, O’Byrne P, Pageau R, Renzi PM. 2009

Safety, pharmacodynamics and pharmacokinetics of TPI 1020 in smokers with asthma

Respiratory Medicine

Gauvreau GM, Boulet L-P, Cockcroft DW, Baatjes A, Cote J, Deschesnes F, Davis B, Strinich T, Howie K, Duong M, Watson RM, Renzi PM, O'Byrne, PM. 2008 Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses

American Journal of Respiratory and Critical Care Medicine

Duong M, Cockcroft D, Boulet L-P, Ahmed T, Iverson H, Atkinson D, Stahl E, Watson R, Davis B, Milo J, Gauvreau G, O'Byrne P. 2008

The effect of IVX-0142, a heparin-derived hypersulfated disaccharide, on the allergic airway responses in asthma

Allergy

Boulet LP , Prince P , Turcotte H , Lemière C, Olivenstein R, Laprise C, Larivee P , Bégin P, Laviolette M. 2006

Clinical features and airway inflammation in mild asthma versus asymptomatic airway hyperresponsiveness

Respiratory Medicine

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