BRONCHOPROVOCATION
- Inhaled allergen (PC20/PD20, early & late asthmatic responses)
- Methacholine airway hyperresponsiveness
- Inhaled mannitol (Aridol®)
- Exercise-induced bronchoconstriction
- Hypertonic saline
- Capsaicin cough challenge
AIRWAY INFLAMMATION MEASUREMENTS
- Sputum induction (cell counts by microscopy or flow cytometry)
- Bronchoscopy
- Blood sampling
- Fractional exhaled nitric oxide
- Bone marrow aspirate
- Skin prick test
- Intradermal allergen challenge
